WebThe "FLASH" radiotherapy maintains tumour control level, suggesting that ultra-high dose rate can substantially enhance the therapeutic window in radiotherapy. The results have … Web14 Apr 2024 · However, the low radiation dose per fraction used in conventional RT seems to be less effective in triggering the so-called radio-vaccination effect . Thus, 1 to 3 large radiation fractions, as high as 8 Gy, in the range of sub-ablative and ultra-hypofractionated schemes, more efficiently induce the interferon type I response [11, 12].
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Web5 Oct 2024 · It is exciting that FLASH radiotherapy (FLASH-RT), as an ultra-high dose rate (UHDR) radiotherapy, has been proposed as a new method in recent years. The FLASH effect was first reported in 1959. However, due to technical limitations, it was relatively challenging to translate the results into clinical practice and further research on this new … Web27 Aug 2024 · Theoretically, these results indicate that FLASH radiotherapy using carbon ions would have a markedly improved therapeutic ratio with greater toxicity in the tumor due to the generation of oxygen at the spread-out Bragg peak. It is well known that molecular oxygen is a product of the radiolysis of water with high-linear energy transfer (LET) … the boys crítica
FLASH radiotherapy: What, how and why? - Research …
Web24 Feb 2024 · Regarding the former, FLASH-RT is a catchy nickname for the novel radiation treatment that uses ultra-high dose rates to deliver radiation therapy (RT). In conventional radiation therapy (CONV-RT) used in most of the world, the dose rate is generally <0.1 Gy/s, whereas the FLASH-RT dose rate is generally defined as a mean dose rate of ≥40 Gy/s [ 8 , … WebUltra-high dose rate FLASH radiation therapy for cancer. Conformality has been a key requirement in radiation therapy for cancer to minimize normal tissue toxicity while … Web11 Apr 2024 · The uncertainty of the WWTPs flow and the population were assumed to be 10% of the mean value and set as normal distribution. The excretion rate of drug was set to lognormal distribution. The daily dose of drugs was set as lognormal distribution and the proportion of the population over 15 years old was set as normal distribution. the boys creador