The secure polypill trial
WebAug 26, 2024 · A three-drug medication known as a "polypill," developed by the Spanish National Center for Cardiovascular Research (CNIC) and Ferrer, is effective in preventing secondary adverse cardiovascular... WebAug 26, 2024 · “Polypill” reduces cardiovascular mortality by 33% in patients treated after a heart attack ... The SECURE trial was funded by the European Union Horizon 2024 research and innovation program ...
The secure polypill trial
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WebAug 15, 2024 · Although a long-term prospective randomized clinical trial, the SECURE study (Secondary prevention of cardiovascular disease in the elderly) it is currently ongoing, for the time being, data about the efficacy of the CNIC-Polypill on MACE in secondary prevention patients are lacking. WebSep 20, 2024 · In the SECURE trial, a polypill containing aspirin, ramipril and atorvastatin taken within 6 months after myocardial infarction reduces the risk of major adverse cardiovascular events compared ...
WebMar 19, 2024 · Prior studies comparing polypill to placebo (Table 1) have also demonstrated superiority of the polypill for BP and LDL-C reduction, but perhaps at the expense of increased risk of adverse events (namely hypotension and dizziness) at higher doses. These trials also found varying degrees of adherence which are likely related to the specific ... WebSep 20, 2024 · In the SECURE trial, a polypill containing aspirin, ramipril and atorvastatin taken within 6 months after myocardial infarction reduces the risk of major adverse …
WebAug 24, 2024 · The PolyIran study was a two-group, pragmatic, cluster-randomised trial nested within the GCS, a cohort study with 50 045 participants aged 40–75 years from the Golestan province in Iran. 20% of GCS participants were enrolled from Gonbad city and 80% from rural areas covering the villages in Gonbad, Aq-Qala, and Kalaleh districts. WebAug 26, 2024 · August 29, 2024. 2024 SECURE TRIAL Polypill Strategy in Secondary Cardiovascular Prevention Phase 3, randomized, controlled clinical trial Objective: To …
WebThe polypill consisted of four low-dose medications: atorvastatin (10 mg), amlodipine (2.5 mg), losartan (25 mg), and hydrochlorothiazide (12.5 mg). Generic versions were placed securely in...
WebAug 26, 2024 · In SECURE, the polypill strategy reduced the risk of cardiovascular death, nonfatal MI, nonfatal ischemic stroke, or urgent revascularization, the study’s primary … spif grantsWebDec 2, 2024 · SECURE will be the first trial testing the efficacy of a fixed dose combination (FDC) polypill for secondary cardiovascular prevention in the elderly population (≥ 65 years old). The main objective is to evaluate the potential benefit of the FDC as a component of a cost-effective, globally available and comprehensive treatment strategy for ... spiffy estates jerseyWebThe use of a polypill in secondary prevention is less controversial because even though no trial has proven its efficacy in this setting, multiple trials show that the individual … personal liabilities examplesWebJun 21, 2024 · Correction: Effectiveness of polypill for prevention of cardiovascular disease (polypars): protocol of a randomized controlled trial. Arch Iran Med. 2024; 24:166. doi: 10.34172/aim.2024.26 Google Scholar; 42. Secondary Prevention of Cardiovascular Disease in the Elderly Trial (SECURE). Accessed May 18, 2024. spiffy\u0027s restaurant newsWebAug 26, 2024 · In the SECURE trial, a treatment strategy for secondary prevention with a polypill containing aspirin, ramipril, and atorvastatin in older patients with recent … spigen cover liquid air compatibilehttp://www.secure-h2024.eu/ personal licence exam questions and answersWebAug 26, 2024 · Recently, the SECURE trial 24 showed that after a median of 3 years of treatment, CV death occurred less frequently among patients in the CNIC-Polypill group compared with those in the usual care ... spigen aquos sense 4 plus