Web31 Mar 2012 · Here, we investigated newly discovered HDAC inhibitors, thailandepsin A (TDP-A) and thailandepsin B (TDP-B), to determine the effects on cell viability, apoptosis … Web28 Oct 2011 · Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities Authors Cheng Wang 1 , …
Extractive fermentation for enhanced production of thailandepsin …
WebThe absolute configuration of thailandepsin A has been determined from the anomalous dispersion and the stereochemistry of all chiral C atoms. Intramolecular N-H O and N-H S … Web11 Jun 2024 · To address this need, we developed and optimized a family of novel unimolecular micelles capable of delivering a newly reported anticancer drug … third place by half full brewery
Thailandepsins: bacterial products with potent histone …
Web21 Jun 2024 · Thailandepsin A (TDP-A) is a novel class I histone deacetylase inhibitor that induces a dose- and time-dependent anti-proliferative effect on human thyroid cancer cells mainly attributed to activation of the extrinsic apoptotic pathway … WebThailandepsin A (TDP-A) is a recently identified HDAC inhibitor with promising therapeutic potential. Discovered by genome mining of the Gram-negative bacterium Burkholderia … WebTo deliver the antitumor peptide, Pep5, to breast tumor cells selectively using a targeting peptide functionalised multi-layered PLGA-PEI nanoparticles. third place books ravenna restaurant