Slp76 flow
WebbSLP76 is a cytosolic adapter protein that functions as a substrate in the T cell receptor (TCR) activation pathway. Upon TCR engagement, SLP76 is phosphorylated on multiple … WebbFC experiment of Jurkat using 12728-1-AP. 1X10^6 Jurkat cells were intracellularly stained with 0.2 ug Anti-Human SLP76 (12728-1-AP) and CoraLite®488-Conjugated AffiniPure …
Slp76 flow
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Webb× Close. The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. WebbSupporting: 1, Mentioning: 20 - Key Points• CD86 mediates myeloma survival via activity from its cytoplasmic tail and the CD28-CD86 interaction facilitates stromal independence.• Blocking the CD28-CD86 pathway is a promising therapeutic avenue for myeloma, as there are already approved agents that target this pathway.Although prognosis for patients …
WebbSH2 domain-containing leukocyte protein of 76 kDa (SLP-76) is a hematopoietic adaptor protein that is important in multiple biochemical signaling pathways and necessary for T … Webb12 jan. 2024 · Here, we identify SLP76 as a binding partner for the cytosolic tail of RAGE both in vitro and in vivo and demonstrate that SLP76 binds RAGE through its sterile α …
WebbThe SLP76-S376A knockin strain was generated by the CIPHE facility ... Antibodies and reagents used for flow cytometry were: CD8-APC, Fixable viability stain 450, antiCD16/32 ... WebbA Life Sciences and Diagnostics business focused on enabling scientists and healthcare professionals to advance research, discovery and detection to improve global health …
WebbSLP-76 is phosphorylated by ZAP-70 downstream of the T cell receptor (TCR). SLP-76 contains an acidic region that includes a PEST domain, …
WebbLysates from control (left panel) and anti-CD3-activated (Cat. No. 555329, right panel) Jurkat cells were probed with purified mouse anti-SLP-76 (pY128) monoclonal antibody … mgb wishbone armWebbSLP76-SH2 was serially diluted from 1 µ m and flowed over the immobilized 14-3-3γ at 30 µL·min −1 for 120 s before allowing dissociation for 6 min. The top SLP76-SH2 … mgbw locationsWebbPhospho-SLP-76 (Tyr145) 2-plate assay protocol. The 2 plate protocol involves culturing cells in a 96-well plate before lysis, then transferring lysates into a 384-well low volume … mgb wire harnessWebbSLP-76 antibody LS-C41105 is an unconjugated mouse monoclonal antibody to human SLP-76 (LCP2) (aa216-434). Validated for Flow, IP and WB. Cited in 1 publication. mgb windshield seal replacementWebbDescription: SLP76 is a cytosolic adapter protein that functions as a substrate in the T cell receptor (TCR) activation pathway. Upon TCR engagement, SLP76 is phosphorylated on … mgb wire wheel paintmgb with acWebbFlow Cytometry (Flow) 5 µL/1x10^6 cells - Visit thermofisher.com to view references and figures. Products are warranted to operate or perform substantially in conformance with published Product specifications in effect at the time of sale, as set forth in the Production documentation, specifications and/or accompanying package inserts ("Documentation"). mgb with hardtop