WebApr 15, 2024 · Cardiac diseases are the foremost cause of morbidity and mortality worldwide. The heart has limited regenerative potential; therefore, lost cardiac tissue cannot be replenished after cardiac injury. Conventional therapies are unable to restore functional cardiac tissue. In recent decades, much attention has been paid to regenerative medicine … WebMyocardin (MYOCD) promotes Smad3-mediated transforming growth factor-β (TGF-β) signaling in mouse fibroblast cells. Our previous studies show that TGF-β/SMADs signaling activation enhances epithelial-mesenchymal transition (EMT) in human non-small cell lung cancer (NSCLC) cells. However, whether and …
Cardiogenic small molecules that enhance myocardial repair …
WebOct 1, 2013 · Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes.Circ Res. 2003; 92:856–864. Link Google Scholar 7. Wang Z, Wang DZ, Pipes GC, Olson EN. Myocardin is a master regulator of smooth muscle gene expression.Proc Natl Acad Sci U S A. 2003; 100:7129–7134. Crossref Medline Google … WebMyocd regulates airway smooth muscle cell remodeling in response to chronic asthmatic injury. MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin. CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding … phoenix open 16th hole attendance
Myocd myocardin [Mus musculus (house mouse)] - Gene - NCBI
WebOct 25, 2024 · Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell. 2001; 105:851–862. doi: 10.1016/s0092-8674(01)00404-4 Crossref Medline Google Scholar; 12. Wang Z, Wang DZ, Pipes GC, Olson EN. Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad … WebJan 13, 2024 · Myocardin is a smooth and cardiac muscle-specific transcriptional coactivator of serum response factor. When expressed ectopically in nonmuscle cells, … WebMyocardin (MYOCD) the most important coactivator of serum response factor (SRF), plays a critical role specifically in the development of cardiac myocytes and vascular smooth muscle cells (VSMCs). Binding of Myocardin to the SRF on the CArG box-containing target genes can transcriptionally activate … Myocardin: A novel player in atherosclerosis phoenix opal location dauntless