Hocek research group
WebMay 24, 2024 · The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal. ... of the modified nick translation assay suggests that at least a subset of the DTT generated nicks contain a 3′-OH group. ... Raindlová, V.; Hocek, M. Scope and limitations of the nicking enzyme amplification … WebA series of new pyrimido[4,5-b]indole ribonucleosides bearing phenyl or hetaryl group at position 4 has been prepared by selective Pd-catalyzed cross-coupling reactions of the corresponding protected 4,6-dichloropyrimido[4, 5-b]indole ribonucleoside with (het)arylboronic acids or stannanes followed by deprotection.
Hocek research group
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WebJun 2, 2015 · To expand the chemical functionality of DNAzymes and aptamers, several new modified deoxyuridine triphosphates have been synthesized. An important precursor that enables this aim is 5-aminomethyl dUTP, whereby the pendent amine serves as a handle for further synthetic functionalization. Five functional groups were conjugated to 5 … http://hocekgroup.uochb.cas.cz/members/menova.html
WebDec 7, 2024 · Encouraging collaboration: International Advisory Board member and former Editorial Board Co-Chair Michal Hocek introduces the Special Collection on Chemistry in the Czech Republic, and outlines how the multidisciplinary focus of ChemPlusChem promotes collaboration on many levels. This Special Collection was launched to honor the 100th … WebSep 2, 2024 · Modified nucleic acids, also called xeno nucleic acids (XNAs), offer a variety of advantages for biotechnological applications and address some of the limitations of first-generation nucleic acid therapeutics. Indeed, several therapeutics based on modified nucleic acids have recently been approved and many more are under clinical evaluation. …
Web2024-2024 Postdoctoral research, Charles University in Prague, Czech Republic, (supervisor Assist. Prof. Eliška Matoušová). since 2024 Postdoctoral research, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Prof. Michal Hocek). List of publications: WebJun 27, 2024 · As a result, protecting group-free strategies to effect glycosylations are available thanks to the tremendous efforts of many research groups. In this review, we showcase the methods available for the selective activation of the anomeric center on the glycosyl donor and the mechanisms by which the glycosylation reactions take place to ...
WebThe Hocek group currently consists of 3 staff scientists, 2 postdocs, 21 PhD students and several undergrad students. Group research interests: Novel types of modified derivatives …
WebMay 1, 2006 · [40] [41][42][43][44][45][46] The Hocek research group has thoroughly evaluated the impact of major groove nucleobase modifications on REs, and a few examples are presented here. Macíčková ... cook junior junior\\u0027s cookin\\u0027 jazzland 958WebMichal Hocek research group. cook junior junior\u0027s cookin\u0027 jazzland 958WebNov 4, 2024 · One fully funded postdoc position is available in Prof. Michal Hocek group starting from January 2024 (or as soon as possible thereafter).. The candidate will join an international multidisciplinary team of the Joint Laboratory of Bioorganic and Medicinal Chemistry of Nucleic Acids of the Institute of Organic Chemistry and Biochemistry (IOCB … cook k-jets-7019-sivfWebThe Hocek group is interested in synthetic, bioorganic and medicinal chemistry of nucleic acids and their components. Novel types of modified derivatives and analogues of nucleobases, nucleosides,… tatuus f4-t-421http://hocekgroup.uochb.cas.cz/members/pablo.html cook krupsWebDec 7, 2024 · Prof. Dr. Michal Hocek. [email protected]; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nam 2, Prague, 16610 Czech … tatuus fa01 imola setuptatuus fa01 real life