Carbonyl cyanide chlorophenylhydrazone
WebCarbonyl cyanide 3-chlorophenylhydrazone (CCCP), a member of the lipophilic weak acid class, is known as an efflux pump inhibitor for Mycobacterium tuberculosis. The aim … WebCell Signaling Technology Inc carbonyl cyanide 3 chlorophenylhydrazone cccp Carbonyl Cyanide 3 Chlorophenylhydrazone Cccp, supplied by Cell Signaling Technology Inc, …
Carbonyl cyanide chlorophenylhydrazone
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WebCorrelative light-electron microscopy revealed that majority of the extracellular mitochondria are in free form and, on rare occasions, some are enclosed in membrane-surrounded vesicles. Rotenone- and carbonyl cyanide m-chlorophenylhydrazone-induced mitochondrial quality impairment promotes the extracellular release of depolarized … WebThe effect of carbonyl cyanide 3-chlorophenylhydrazone combined with colistin was used to test efflux pump involvement. Patient treatment outcomes were also reported. Results: The most prevalent infection in CoR-AB patients was pneumonia (35.3%), and all patients were administered colistin combined with another agent. The 30-day mortality was ...
WebThis report aims to explore how Bcl-xL, a Bcl-2 family protein, regulates PINK1/Parkin-dependent mitophagy. Compared with the Hela cells expressing Parkin alone, co-expression of Bcl-xL significantly inhibited CCCP (Carbonyl cyanide 3- chlorophenylhydrazone)-induced mitochondrial Parkin accumulation and mitophagy. WebCarbonyl cyanide 3-chlorophenylhydrazone ≥97% (TLC), powder Synonym (s): m-Cl-CCP, CCCP, Mesoxalonitrile 3-chlorophenylhydrazone Empirical Formula (Hill …
WebDec 16, 2011 · Carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial uncoupler, leads to AMPK activation and Parkin-dependent mitophagy, respectively. … WebROS generation from mitochondria is a vital factor in an uncoupler, carbonyl cyanide m -chlorophenylhydrazone (CCCP)-induced autophagy [82]. An LC3-interacting region in …
WebJul 31, 2024 · Recently, we designed an inventive paradigm in nanomedicine—drug-free macromolecular therapeutics (DFMT). The ability of DFMT to induce apoptosis is based on biorecognition at cell surface, and crosslinking of receptors without the participation of low molecular weight drugs. The system is composed of two nanoconjugates: a bispecific …
WebAug 13, 2024 · Mitochondrial toxins, such as rotenone, and carbonyl cyanide m-chlorophenylhydrazone (CCCP), which is an uncoupler of mitochondrial oxidative phosphorylation induce loss of membrane potential... htupaWebDescription. CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone), an oxidative phosphorylation inhibitor, is a protonophore … htun meaningWebMenadione sodium bisulfite (MSB) increased the oxygen consumption rates in both cell lines, whereas CCCP (carbonyl cyanide m-chlorophenylhydrazone) stimulated the oxygen consumption rates only in WT Molt-4 cells. Superoxide radical adducts were observed in both WT and rho (0) cells when stimulated with MSB. htun yatiWebDec 17, 2024 · The effect of the efflux pump inhibitor Carbonyl Cyanide m-Chlorophenylhydrazone (CCCP) on the susceptibility to imipenem and cefepime in clinical strains of Acinetobacter baumannii In conclusion, our results demonstrate that the use of CCCP may improve the antibiotic effect of imipenem and cefepime on clinical strains of … htut khaung music entertainmentWebAbbreviations: ATG, autophagy related; CALCOCO2/NDP52, calcium binding and coiled-coil domain 2; CCCP, carbonyl cyanide chlorophenylhydrazone; CYCS, cytochrome c, somatic; HSPD1/HSP60, heat shock protein family D (Hsp60) member 1; IMM, inner mitochondrial membrane; MAP1LC3/LC3, microtubule associated protein 1 light chain 3; … htus zadarWebCarbonyl Cyanide m-Chlorophenyl Hydrazone / pharmacology* Cell Size / drug effects Cyclosporine / pharmacology* Ischemic Preconditioning, Myocardial / methods Microscopy, Electron Myocytes, Cardiac / cytology Myocytes, Cardiac / drug effects* Rabbits Time Factors Uncoupling Agents / pharmacology* Substances Uncoupling Agents hturk turklaw.orgWebProduct name : Carbonyl cyanide 3-chlorophenylhydrazone Product Number : C2759 Brand : Sigma CAS-No. : 555-60-2 1.2 Relevant identified uses of the substance or … htun surname