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WebShare your videos with friends, family, and the world WebPeople named Capice Smith. Find your friends on Facebook. Log in or sign up for Facebook to connect with friends, family and people you know. Log In. or. Sign Up. … CAPICE is a general prediction method that provides pathogenicity estimations for SNVs and InDels across different molecular consequences. We used the same set of features that the CADD score was built upon and trained a gradient-boosting tree model directly on the variant pathogenicity. See more An overview of the training and benchmark datasets can be found in Table 1. Training and benchmark data on neutral and pathogenic variants … See more The collected variants in both the training and test datasets were annotated using CADD web service v1.4, which consists of 92 different features from VEP (version 90.5) [33] and epigenetic information from ENCODE [34] and … See more To build a benchmark dataset for performance evaluation that was fully independent of model construction procedures, we selected high-confidence pathogenic variants … See more We trained a gradient-boosting tree model using the XGBoost (version 0.72) Python package. The hyper-parameters, n_estimators, max_depth, and learning_rate were selected by 5-fold cross-validation … See more town of jonesville virginia